Job Description

Job Family:
Scientist

Travel Required:
None

Clearance Required:
Ability to Obtain Public Trust

What You Will Do:

We are looking for a Molecular Biologist (Virology Core Biological Scientist) to support the Vaccine Research Center (VRC) at NIAID by performing advanced protein engineering, purification, and characterization work in support of virology and immunology research. This is a full-time position located in Bethesda, MD.

• Design and optimize recombinant protein expression systems for multiple host platforms.
• Perform protein purification and characterization using biochemical and biophysical assays.
• Conduct protein-antibody interaction studies and analyze kinetic data.
• Support structure prediction, molecular modeling, and data visualization efforts.
• Operate and maintain laboratory instrumentation, including FPLC, BLI, and SPR systems.
• Maintain laboratory inventory, documentation, and standard operating procedures (SOPs).
• Analyze experimental data and support reporting through presentations and manuscripts.
• Collaborate with NIH investigators and multidisciplinary research teams.

What You Will Need:

• Master's degree
• A minimum of THREE (3) years of experience in molecular biology, protein engineering, or related laboratory research.
• Demonstrated expertise in protein production and purification techniques, including aseptic technique, chromatography, and molecular characterization.
• Demonstrated proficiency in kinetic analysis, including hands-on experience with BLI or SPR.
• Ability to operate and maintain protein purification and analytical instrumentation.
• Familiarity with molecular visualization tools such as PyMOL, ChimeraX, or AlphaFold.
• Strong collaboration, communication, and organizational skills to support multidisciplinary teams.
• Proficiency with Microsoft Office Suite and scientific software tools.
• Must be able to obtain and maintain a Federal or DoD "public trust"; candidates must receive approved adjudication prior to onboarding with Guidehouse. Candidates with an active public trust or suitability are preferred.

What Would Be Nice To Have:

• Ph.D. in Biochemistry, Molecular Biology, Chemical Engineering, or a closely related biomedical field preferred.
• Background working with recombinant protein-antibody interaction studies and assay development.
• Exposure to advanced protein engineering strategies and chimeric protein design.
• Familiarity with high-throughput kinetic platforms and epitope binning techniques.
• Ability to support data visualization and structural modeling for scientific communication.

The annual salary range for this position is $74,000.00-$124,000.00. Compensation decisions depend on a wide range of factors, including but not limited to skill sets, experience and training, security clearances, licensure and certifications, and other business and organizational needs.

What We Offer:

Guidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.

Benefits include:

• Medical, Rx, Dental & Vision Insurance
• Personal and Family Sick Time & Company Paid Holidays
• Parental Leave
• 401(k) Retirement Plan
• Group Term Life and Travel Assistance
• Voluntary Life and AD&D Insurance
• Health Savings Account, Health Care & Dependent Care Flexible Spending Accounts
• Transit and Parking Commuter Benefits
• Short-Term & Long-Term Disability
• Tuition Reimbursement, Personal Development, Certifications & Learning Opportunities
• Employee Referral Program
• Corporate Sponsored Events & Community Outreach
• Care.com annual membership
• Employee Assistance Program
• Supplemental Benefits via Corestream (Critical Care, Hospital Indemnity, Accident Insurance, Legal Assistance and ID theft protection, etc.)
• Position may be eligible for a discretionary variable incentive bonus

About Guidehouse

Guidehouse is an Equal Opportunity Employer-Protected Veterans, Individuals with Disabilities or any other basis protected by law, ordinance, or regulation.

Guidehouse will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of applicable law or ordinance including the Fair Chance Ordinance of Los Angeles and San Francisco.

If you have visited our website for information about employment opportunities, or to apply for a position, and you require an accommodation, please contact Guidehouse Recruiting at [click to reveal phone number]1-571-633-1711 or via email at [click to reveal email address] RecruitingAccommodation@guidehouse.com . All information you provide will be kept confidential and will be used only to the extent required to provide needed reasonable accommodation.

All communication regarding recruitment for a Guidehouse position will be sent from Guidehouse email domains including @guidehouse.com or [click to reveal email address] guidehouse@myworkday.com . Correspondence received by an applicant from any other domain should be considered unauthorized and will not be honored by Guidehouse. Note that Guidehouse will never charge a fee or require a money transfer at any stage of the recruitment process and does not collect fees from educational institutions for participation in a recruitment event. Never provide your banking information to a third party purporting to need that information to proceed in the hiring process.

If any person or organization demands money related to a job opportunity with Guidehouse, please report the matter to Guidehouse's Ethics Hotline. If you want to check the validity of correspondence you have received, please contact [click to reveal email address] recruiting@guidehouse.com . Guidehouse is not responsible for losses incurred (monetary or otherwise) from an applicant's dealings with unauthorized third parties.

Guidehouse does not accept unsolicited resumes through or from search firms or staffing agencies. All unsolicited resumes will be considered the property of Guidehouse and Guidehouse will not be obligated to pay a placement fee.

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