Job Description

Research Associate II – In vivo Electrophysiology & Behavior

The Allen Institute accelerates science for a healthier world through large-scale research designed to answer some of the most complex questions in biology. Our multi-disciplinary teams generate foundational knowledge, tools, and data to understand how our brain, cells, and immune system work. We share our work openly so others can build on it, move faster, and ask bigger questions. We drive discovery forward and create new possibilities for improving human health.

The goal of the Neural Dynamics accelerator is to understand how the brain generates flexible behavior. We aim to uncover the algorithms—implemented by dynamics in brain-wide neural circuits—that allow animals to build internal models, process information, and choose actions.

We are seeking a Research Associate to contribute to projects seeking to decipher the neural mechanisms of flexible decision-making in mice. This position will leverage state-of-the-art electrophysiological methods, such as Neuropixels probes, as well as molecular and transgenic tools. The goal is to record simultaneously from many anatomically connected regions while mice are engaged in a variety of cognitive tasks. The ideal candidate will be team-oriented and have extensive experience in electrophysiological techniques. The Research Associate will work alongside a diverse team of Scientists, Technicians, Engineers, and Investigators, and so collaboration and communication skills are key.

At the Allen Institute, we believe that science is for everyone – and should be open to everyone. We are dedicated to combating biases and reducing barriers to STEM careers more broadly.

We also believe that science is better when it includes different perspectives and voices. We strive to make the Allen Institute a place where everyone feels like they belong and are empowered to do their best work in a supportive environment.

We are an equal-opportunity employer and strongly encourage people from all backgrounds to apply for our open positions.

Essential Functions

• Perform experiments using in vivo electrophysiology, carefully controlled mouse behavior, and neural manipulations
• Collaborate with scientists to develop and evaluate new behavioral tasks and associated methods for data collection, quantification, and analysis
• Collaborate internally and externally to analyze physiology and behavior data
• Additional tasks may include histology and/or surgery
• Participate in weekly lab meetings
• Train team members to perform procedures

*Note: Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. This description reflects management’s assignment of essential functions; it does not proscribe or restrict the tasks that may be assigned.*

Required Education and Experience

• Bachelor's degree in Neuroscience, Biology, or related discipline
• 2 years of relevant experience

Preferred Education and Experience

• 3 years of experience with in vivo electrophysiology in rodent models
• Surgical experience in rodents
• Rodent handling and training experience
• Ability to write reusable code in Python or Matlab

Work Environment

• May enter laboratory environment, including potential exposure to lasers, biohazards
• Exposure to and handling of laboratory animals required

Animal Care Services

• Daily exposure to and handling of laboratory animals required
• Pre and post-operative care for mice
• Administration of compounds to mice (iv, ip, sc, po, im, ro, icv)
• Perform health assessments of mice
• Perform euthanasia and tissue collections
• Perform daily vivarium maintenance and/or closing procedures

Physical Demands

• Fine motor movements in fingers/hands to operate computers and other office equipment; repetitive motion with lab equipment
• Stooping, bending, crouching
• Reaching, or climbing ladders

Position Type/Expected Hours of Work

• This role is currently working onsite and is expected to work onsite for the majority of working hours. The primary work location for this role is 615 Westlake Ave N., with the flexibility to work remotely on a limited basis.

Additional Eligibility Qualifications

• All employees who work with live animals must complete an Occupational Health medical history form and/or consultation with an Occupational Health Provider and receive clearance to work with animals. Depending on your health history and job responsibilities, an annual respiratory health screening and clearance to use a respirator may also be required.

Additional Comments

• **Please note, this opportunity does not offer work visa sponsorship**

Annualized Salary Range

• $66,500 - $81,350 *

* Final salary depends on the required education for the role, experience, level of skills relevant to the role, and work location, where applicable.

Benefits

• Employees (and their families) are eligible to enroll in benefits per eligibility rules outlined in the Allen Institute’s Benefits Guide. These benefits include medical, dental, vision, and basic life insurance. Employees are also eligible to enroll in the Allen Institute’s 401k plan. Paid time off is also available as outlined in the Allen Institutes Benefits Guide. Details on the Allen Institute’s benefits offering are located at the following link to the Benefits Guide: https://alleninstitute.org/careers/benefits.

It is the policy of the Allen Institute to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by federal, state or local law. In addition, the Allen Institute will provide reasonable accommodations for qualified individuals with disabilities.

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